Contribution of Environmental Toxicants and Lifestyle in Development of Cardiovascular Diseases
Abstract
Environmental pollutants and lifestyle factors are significantly contribute to the development of cardiovascular diseases (CVD), which are the major cause of mortality and morbidity worldwide. Exposure of heavy metals such as lead, chromium and Arsenic particulate matter (PM 2.5 and PM 10), and persistent organic pollutants like dichloro diphenyl trichloroethane and dichlorodiphenyl dichloroethylene are critical factors affecting cardiovascular health and cause CVD. Evidence suggests that these pollutants and various lifestyle choices such as smoking, and physical inactivity, activates multiple pathways including oxidative stress, systemic inflammation, and endothelial dysfunction thereby increasing risk of CVD. This review aims to critically analyze the complex relationship between environmental contaminants and sedentary lifestyle and their involvement in CVD risk.
Keywords: Lifestyle Factors; Pesticides; Environmental Toxins; Cardiovascular Diseases
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DOI: http://dx.doi.org/10.62940/als.v12i4.3720
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